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The bone marrow is found in the cavities in the center of the long bones in your body. Blood cells are produced in the bone marrow. White blood cells (WBC) fight infection. Red blood cells (RBC) carry oxygen and platelets (PLT) help to clot formation to prevent bleeding.
What is a stem cell?
Stem cells are self-renewing and differentiating cells that are not present in any cell other than living organisms. Stem cells, when needed, differentiate them from the next to the cells, allowing the development, maturation and proliferation of the cells.
Stem cells are called embryonic stem cells, adult stem cells and induced pluripotent stem cells. Hematopoietic stem cells from adult stem cells are used in stem cell transplantation. Stem cells are also of great interest in non-hematological areas. In particular, stem cell therapies that are applied experimentally in cardiological and neurological diseases are the leading.
Stem cells are new immature blood cells. All blood cells begin as a stem cell. Thus, with stem cell transplantation, we can regenerate your blood cell formation skills. Stem cells tend to remain in the bone marrow, where the body can become any type of blood cell, but some are involved in the general circulation in blood vessels.
Stem Cell Transplantation is applied in the treatment of diseases?
Various organ cancers,
Inadequate functioning of bone marrow,
It is applied in the treatment of hereditary metabolic diseases.
How to obtain Stem Cells?
The stem cell can be obtained from bone marrow, peripheral blood or cord blood. Stem cell harvesting from the bone marrow is performed under general or local anesthesia with a special needle by entering the donor’s hip bone once. Stem cell harvesting from peripheral blood is performed by transferring the stem cells located in the bone marrow into the bloodstream and then collecting with the apheresis device by applying a special drug called growth factor to the donor. Although bone marrow is used as a stem cell source in the first transplants in history, 75% of the patients have peripheral blood stem cell transplantation.
If the stem blood from the cord blood is born, the baby is collected in the blood bag in 2-4 minutes with the help of the injector after the cord is cut. The collected stem cells are stored at 80 ° C-196 ° C using programmed or mechanical freezing methods by adding DMSO to the cryoprotectant substance under sterile conditions.
For more information about Koç University Hospital Bone Marrow Transplantation Center, click on the link.
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